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Issue 4, 2015
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Lab on a chip for continuous-flow magnetic cell separation

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Abstract

Separation of cells is a key application area of lab-on-a-chip (LOC) devices. Among the various methods, magnetic separation of cells utilizing microfluidic devices offers the merits of biocompatibility, efficiency, and simplicity. This review discusses the fundamental physics involved in using magnetic force to separate particles, and identifies the optimisation parameters and corresponding methods for increasing the magnetic force. The paper then elaborates the design considerations of LOC devices for continuous-flow magnetic cell separation. Examples from the recently published literature illustrate these state-of-the-art techniques.

Graphical abstract: Lab on a chip for continuous-flow magnetic cell separation

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Publication details

The article was received on 04 Dec 2014, accepted on 16 Dec 2014 and first published on 16 Dec 2014


Article type: Critical Review
DOI: 10.1039/C4LC01422G
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Lab Chip, 2015,15, 959-970

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    Lab on a chip for continuous-flow magnetic cell separation

    M. Hejazian, W. Li and N. Nguyen, Lab Chip, 2015, 15, 959
    DOI: 10.1039/C4LC01422G

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