Jump to main content
Jump to site search

Issue 2, 2015
Previous Article Next Article

An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of individual cells

Author affiliations

Abstract

In this work we present a centrifugal microfluidic system enabling highly efficient collective trapping and alignment of particles such as microbeads and cells, their multi-colour fluorescent detection and subsequent manipulation by optical tweezers. We demonstrate array-based capture and imaging followed by “cherry-picking” of individual particles, first for fluorescently labelled polystyrene (PS) beads and then for cells. Different cell lines are discriminated based on intracellular as well as surface-based markers.

Graphical abstract: An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of individual cells

Back to tab navigation

Supplementary files

Article information


Submitted
28 Aug 2014
Accepted
17 Oct 2014
First published
12 Nov 2014

Lab Chip, 2015,15, 378-381
Article type
Technical Innovation

An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of individual cells

R. Burger, D. Kurzbuch, R. Gorkin, G. Kijanka, M. Glynn, C. McDonagh and J. Ducrée, Lab Chip, 2015, 15, 378
DOI: 10.1039/C4LC01002G

Social activity

Search articles by author

Spotlight

Advertisements