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Issue 23, 2015
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Metal nanoclusters: novel probes for diagnostic and therapeutic applications

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Abstract

Metal nanoclusters, composed of several to a few hundred metal atoms, have received worldwide attention due to their extraordinary physical and chemical characteristics. Recently, great efforts have been devoted to the exploration of the potential diagnostic and therapeutic applications of metal nanoclusters. Here we focus on the recent advances and new horizons in this area, and introduce the rising progress on the use of metal nanoclusters for biological analysis, biological imaging, therapeutic applications, DNA assembly and logic gate construction, enzyme mimic catalysis, as well as thermometers and pH meters. Furthermore, the future challenges in the construction of biofunctional metal nanoclusters for diagnostic and therapeutic applications are also discussed. We expect that the rapidly growing interest in metal nanocluster-based theranostic applications will certainly not only fuel the excitement and stimulate research in this highly active field, but also inspire broader concerns across various disciplines.

Graphical abstract: Metal nanoclusters: novel probes for diagnostic and therapeutic applications

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Publication details

The article was received on 04 Aug 2015 and first published on 24 Sep 2015


Article type: Review Article
DOI: 10.1039/C5CS00607D
Chem. Soc. Rev., 2015,44, 8636-8663

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    Metal nanoclusters: novel probes for diagnostic and therapeutic applications

    Y. Tao, M. Li, J. Ren and X. Qu, Chem. Soc. Rev., 2015, 44, 8636
    DOI: 10.1039/C5CS00607D

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