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Issue 3, 2015
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Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization

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Abstract

The stimuli-responsive polypeptides have drawn extensive attention because of their promising applications in biotechnology considering their biocompatibility, biodegradability, and bioactivity. In this tutorial review, we summarize the most recent progress in this area, including thermo-, redox-, photo-, and biomolecule responsive polypeptides over the past decade. The design and synthesis of stimuli-responsive polypeptides will be briefly introduced. The correlation between the structure and properties, particularly the effects of polypeptide conformation, will be emphasized here. In addition, the applications of stimuli-responsive polypeptides in controlled drug release and tissue engineering are briefly discussed.

Graphical abstract: Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization

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Publication details

The article was received on 08 Aug 2014 and first published on 22 Oct 2014


Article type: Tutorial Review
DOI: 10.1039/C4CS00271G
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Chem. Soc. Rev., 2015,44, 612-622

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    Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization

    Y. Shen, X. Fu, W. Fu and Z. Li, Chem. Soc. Rev., 2015, 44, 612
    DOI: 10.1039/C4CS00271G

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