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Issue 24, 2015
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Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors

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Abstract

Whereas spatial organisation of function is ubiquitous in biology, it has been lacking in artificial cells. We rectify this by using multi-compartment vesicles as chassis for artificial cells, allowing distinct biological processes to be isolated in space. This is demonstrated by in vitro synthesis of two proteins in predefined vesicle regions.

Graphical abstract: Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors

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Publication details

The article was received on 17 Dec 2014, accepted on 17 Mar 2015 and first published on 01 May 2015


Article type: Communication
DOI: 10.1039/C4CP05933F
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Phys. Chem. Chem. Phys., 2015,17, 15534-15537
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    Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors

    Y. Elani, R. V. Law and O. Ces, Phys. Chem. Chem. Phys., 2015, 17, 15534
    DOI: 10.1039/C4CP05933F

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