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Issue 77, 2015
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A peptide-based pH-sensitive drug delivery system for targeted ablation of cancer cells

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Abstract

A peptide-guided prodrug incorporating a tumor-specific peptide, doxorubicin, and a pH-sensitive hydrazone bridge was developed for targeted ablation of cancer cells with minimal side cytotoxicity.

Graphical abstract: A peptide-based pH-sensitive drug delivery system for targeted ablation of cancer cells

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Supplementary files

Article information


Submitted
24 Jun 2015
Accepted
05 Aug 2015
First published
05 Aug 2015

Chem. Commun., 2015,51, 14454-14457
Article type
Communication

A peptide-based pH-sensitive drug delivery system for targeted ablation of cancer cells

Y. Jin, Y. Huang, H. Yang, G. Liu and R. Zhao, Chem. Commun., 2015, 51, 14454
DOI: 10.1039/C5CC05184C

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