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Issue 74, 2015
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Recent trends in the development of vitamin B12 derivatives for medicinal applications

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Abstract

This Feature Article highlights recent developments in the field of vitamin B12 derivatives for medicinal applications. The following topics are emphasized: (1) the development of aquacorrinoids for cyanide detection and detoxification, (2) the use of vitamin B12 conjugates and (3) antivitamins B12 for therapy and diagnosis, and (4) the design of corrinoids as activators of soluble guanylyl cyclase (sGC).

Graphical abstract: Recent trends in the development of vitamin B12 derivatives for medicinal applications

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Article information


Submitted
11 Jun 2015
Accepted
16 Jul 2015
First published
16 Jul 2015

Chem. Commun., 2015,51, 14004-14017
Article type
Feature Article

Recent trends in the development of vitamin B12 derivatives for medicinal applications

F. Zelder, Chem. Commun., 2015, 51, 14004
DOI: 10.1039/C5CC04843E

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