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Issue 54, 2015
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Human serum biomarker detection based on a cascade signal amplification strategy by a DNA molecule machine

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Abstract

A convenient method is presented that employs a DNA machine for protein biomarker detection. The detection limit is 400 times lower compared to the method without a DNA machine. This study provides a promising method that could realize most protein biomarker detections without the corresponding aptamers, using a DNA machine for signal amplification.

Graphical abstract: Human serum biomarker detection based on a cascade signal amplification strategy by a DNA molecule machine

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Supplementary files

Article information


Submitted
07 May 2015
Accepted
28 May 2015
First published
29 May 2015

Chem. Commun., 2015,51, 10843-10846
Article type
Communication
Author version available

Human serum biomarker detection based on a cascade signal amplification strategy by a DNA molecule machine

J. Liu, X. Xin, H. Zhou and S. Zhang, Chem. Commun., 2015, 51, 10843
DOI: 10.1039/C5CC03823E

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