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Issue 59, 2015
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A red-emitting ratiometric fluorescent probe based on a benzophosphole P-oxide scaffold for the detection of intracellular sodium ions

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Abstract

We disclose the development of a ratiometric fluorescent probe based on a benzophosphole P-oxide and its application for the detection of intracellular Na+ ions. Excitation by visible light induced red emission from this probe in water, which was subjected to a hypsochromic shift upon complexation with Na+. Based on this change, a ratiometric analysis enabled us to visualise changes in the Na+ concentration in living mammalian cells.

Graphical abstract: A red-emitting ratiometric fluorescent probe based on a benzophosphole P-oxide scaffold for the detection of intracellular sodium ions

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Article information


Submitted
28 Apr 2015
Accepted
17 Jun 2015
First published
17 Jun 2015

Chem. Commun., 2015,51, 11880-11883
Article type
Communication
Author version available

A red-emitting ratiometric fluorescent probe based on a benzophosphole P-oxide scaffold for the detection of intracellular sodium ions

M. Taki, H. Ogasawara, H. Osaki, A. Fukazawa, Y. Sato, K. Ogasawara, T. Higashiyama and S. Yamaguchi, Chem. Commun., 2015, 51, 11880
DOI: 10.1039/C5CC03547C

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