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Issue 44, 2015
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Guanosine radical reactivity explored by pulse radiolysis coupled with transient electrochemistry

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Abstract

We follow the reactivity of a guanosine radical created by a radiolytic electron pulse both by spectroscopic and electrochemical methods. This original approach allows us to demonstrate that there is a competition between oxidation and reduction of these intermediates, an important result to further analyse the degradation or repair pathways of DNA bases.

Graphical abstract: Guanosine radical reactivity explored by pulse radiolysis coupled with transient electrochemistry

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Article information


Submitted
16 Mar 2015
Accepted
12 Apr 2015
First published
14 Apr 2015

Chem. Commun., 2015,51, 9089-9092
Article type
Communication
Author version available

Guanosine radical reactivity explored by pulse radiolysis coupled with transient electrochemistry

A. Latus, M. S. Alam, M. Mostafavi, J.-L. Marignier and E. Maisonhaute, Chem. Commun., 2015, 51, 9089
DOI: 10.1039/C5CC02211H

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