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Issue 37, 2015
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Facile synthesis of nucleic acid–polymer amphiphiles and their self-assembly

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Abstract

A solid-phase synthesis for nucleic acid–polymer amphiphiles is developed. Using this strategy, several DNA-b-polymer amphiphiles are synthesized, and their self-assembly in aqueous solution is investigated. This general method can in principle be extended to nearly all polymers synthesized by atom transfer radical polymerization to produce a variety of nucleic acid–polymer conjugates.

Graphical abstract: Facile synthesis of nucleic acid–polymer amphiphiles and their self-assembly

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Supplementary files

Article information


Submitted
07 Mar 2015
Accepted
31 Mar 2015
First published
31 Mar 2015

Chem. Commun., 2015,51, 7843-7846
Article type
Communication
Author version available

Facile synthesis of nucleic acid–polymer amphiphiles and their self-assembly

F. Jia, X. Lu, X. Tan and K. Zhang, Chem. Commun., 2015, 51, 7843
DOI: 10.1039/C5CC01934F

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