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Issue 18, 2015
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Enzyme-driven i-motif DNA folding for logic operations and fluorescent biosensing

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Abstract

DNA nanodevices capable of “NOR” and “NAND” logic operations were developed using enzymatic reactions to generate an acidic pH gradient and drive the conformation change of cytosine-rich DNA. Due to the high selectivity and sensitivity of the enzymatic reactions in driving DNA logic gates, novel fluorescent biosensors were further designed for enzyme activity assay and glucose sensing.

Graphical abstract: Enzyme-driven i-motif DNA folding for logic operations and fluorescent biosensing

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Supplementary files

Article information


Submitted
11 Dec 2014
Accepted
27 Jan 2015
First published
27 Jan 2015

Chem. Commun., 2015,51, 3812-3815
Article type
Communication
Author version available

Enzyme-driven i-motif DNA folding for logic operations and fluorescent biosensing

M. Wang, G. Zhang and D. Zhang, Chem. Commun., 2015, 51, 3812
DOI: 10.1039/C4CC09905B

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