This website uses cookies to give you the best user experience. If you continue without changing your settings we'll assume you are happy to receive all RSC cookies. You can change your cookie settings by navigating to our Privacy and Cookies page and following the instructions. These instructions are also obtainable from the privacy link at the bottom of any RSC page.
Lite Version|Standard version
Home > Chemical Communications >
Download
PDF
Rich HTML
Abstract | Cited by

DC-SIGN antagonists were designed combining one selective monovalent glycomimetic ligand with trivalent dendrons separated by a rigid core of controlled length. The design combines multiple multivalency effects to achieve inhibitors of HIV infection, which are active in nanomolar concentration.

Graphical abstract: Designing nanomolar antagonists of DC-SIGN-mediated HIV infection: ligand presentation using molecular rods

Page: ^ Top


Enter Keywords, author, title,reference, or DOI
Log in | Register