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Issue 9, 2015
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Synthesis of imidazo[1,2-a]pyridines: a decade update

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Abstract

Imidazopyridine is one of the important fused bicyclic 5–6 heterocycles and it is recognized as a “drug prejudice” scaffold due to its wide range of applications in medicinal chemistry. This moiety is also useful in material science because of its structural character. Synthesis of this moiety from the easily available chemicals is desirable due to its tremendous use in the various branches of chemistry. Here we report a review on the synthesis of this scaffold employing different strategies such as condensation, multicomponent reactions, oxidative coupling, tandem reactions, aminooxygenation, and hydroamination reactions.

Graphical abstract: Synthesis of imidazo[1,2-a]pyridines: a decade update

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Publication details

The article was received on 28 Oct 2014, accepted on 06 Nov 2014 and first published on 06 Nov 2014


Article type: Feature Article
DOI: 10.1039/C4CC08495K
Chem. Commun., 2015,51, 1555-1575

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    Synthesis of imidazo[1,2-a]pyridines: a decade update

    A. K. Bagdi, S. Santra, K. Monir and A. Hajra, Chem. Commun., 2015, 51, 1555
    DOI: 10.1039/C4CC08495K

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