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Issue 8, 2015
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A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse

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Abstract

A very fast-responsive fluorescent probe PZ–Py for imaging mitochondrial HClO/ClO, with a relatively long emission wavelength, was prepared. The limit of detection was evaluated to be 17.9 nM. Moreover, the probe PZ–Py was successfully applied in the imaging of endogenous HClO/ClO in the mitochondria of RAW 264.7 cells and living nude mouse.

Graphical abstract: A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse

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Publication details

The article was received on 19 Sep 2014, accepted on 20 Nov 2014 and first published on 02 Dec 2014


Article type: Communication
DOI: 10.1039/C4CC07411D
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Chem. Commun., 2015,51, 1442-1445

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    A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse

    H. Xiao, K. Xin, H. Dou, G. Yin, Y. Quan and R. Wang, Chem. Commun., 2015, 51, 1442
    DOI: 10.1039/C4CC07411D

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