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Issue 17, 2015
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Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

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Abstract

Natural abundance 13C NMR spectra of biological extracts are recorded in a single scan provided that the samples are hyperpolarized by dissolution dynamic nuclear polarization combined with cross polarization. Heteronuclear 2D correlation spectra of hyperpolarized breast cancer cell extracts can also be obtained in a single scan. Hyperpolarized NMR of extracts opens many perspectives for metabolomics.

Graphical abstract: Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

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Publication details

The article was received on 15 Jun 2015, accepted on 20 Jul 2015 and first published on 20 Jul 2015


Article type: Communication
DOI: 10.1039/C5AN01203A
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Analyst, 2015,140, 5860-5863

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    Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

    J. Dumez, J. Milani, B. Vuichoud, A. Bornet, J. Lalande-Martin, I. Tea, M. Yon, M. Maucourt, C. Deborde, A. Moing, L. Frydman, G. Bodenhausen, S. Jannin and P. Giraudeau, Analyst, 2015, 140, 5860
    DOI: 10.1039/C5AN01203A

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