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Issue 13, 2015
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A microfabrication-free nanoliter droplet array for nucleic acid detection combined with isothermal amplification

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Abstract

A nanoliter droplet array based on a hydrophilic–hydrophobic patterned chip is developed without using microfabrication technology. Combined with the isothermal amplification technology, it has been applied to perform nucleic acid detection, showing excellent specificity and sensitivity. As a versatile platform, it is used to detect three gene targets successfully.

Graphical abstract: A microfabrication-free nanoliter droplet array for nucleic acid detection combined with isothermal amplification

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Publication details

The article was received on 24 Mar 2015, accepted on 05 May 2015 and first published on 05 May 2015


Article type: Communication
DOI: 10.1039/C5AN00573F
Analyst, 2015,140, 4370-4373

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    A microfabrication-free nanoliter droplet array for nucleic acid detection combined with isothermal amplification

    X. Ma, W. Xu, C. Chen, Z. Lu and J. Li, Analyst, 2015, 140, 4370
    DOI: 10.1039/C5AN00573F

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