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Issue 2, 2015
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Ratiometric fluorescence detection of cysteine and homocysteine with a BODIPY dye by mimicking the native chemical ligation

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Abstract

The selective detection of cysteine and homocysteine over glutathione and other amino acids was demonstrated with an 8-MeS-BODIPY probe by mimicking the native chemical ligation approach, which allowed the selective and ratiometric fluorescence sensing of cysteine over other biothiols at physiologically relevant concentrations and in different organs of a zebrafish.

Graphical abstract: Ratiometric fluorescence detection of cysteine and homocysteine with a BODIPY dye by mimicking the native chemical ligation

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Article information


Submitted
04 Oct 2014
Accepted
11 Nov 2014
First published
11 Nov 2014

Analyst, 2015,140, 422-427
Article type
Paper
Author version available

Ratiometric fluorescence detection of cysteine and homocysteine with a BODIPY dye by mimicking the native chemical ligation

D. H. Ma, D. Kim, E. Seo, S. Lee and K. H. Ahn, Analyst, 2015, 140, 422
DOI: 10.1039/C4AN01791A

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