Synthesis and properties of the metallo-supramolecular polymer hydrogel poly[methyl vinyl ether-alt-mono-sodium maleate]·AgNO3: Ag+/Cu2+ ion exchange and effective antibacterial activity

Abstract

The commercial polymeric anhydride poly(methyl vinyl ether-alt-maleic anhydride) (PVM/MA) is converted by reaction with NaOH to give poly(methyl vinyl ether-alt-mono-sodium maleate) (PVM/Na-MA). By addition of AgNO₃-solution, the formation of the silver(I) supramolecular polymer hydrogel poly[methyl vinyl ether-alt-mono-sodium maleate]·AgNO₃ is reported. Freeze-dried samples of the hydrogel show a mesoporous network of polycarboxylate ligands that are crosslinked by silver(I) cations. In the intact hydrogel, ion-exchange studies are reported and it is shown that Ag⁺ ions can be exchanged by copper(II) cations without disintegration of the hydrogel. The silver(I) hydrogel shows effective antibacterial activity and potential application as burn wound dressing.