Colloidal Au nanoparticles were first applied for “turn on” fluorescence direct imaging of in-gel proteins after polyacrylamide gel electrophoresis (PAGE). It was successfully used for detecting human proteins after 1-D and 2-D PAGE, providing higher resolution and sensitivity than traditional CBB-R250 imaging.
N. Na, J. Zhang, Y. You, S. Su and J. Ouyang, J. Mater. Chem. B, 2014, 2, 2654 DOI: 10.1039/C3TB21859G
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