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Issue 14, 2014
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On-chip development of hydrogel microfibers from round to square/ribbon shape

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Abstract

We use a microfluidic approach to fabricate gelatin fibers with controlled sizes and cross-sections. Uniform gelatin microfibers with various morphologies and cross-sections (round and square) are fabricated by increasing the gelatin concentration of the core solution from 8% to 12%. Moreover, the increase of gelatin concentration greatly improves the mechanical properties of gelatin fibers; the Young's modulus and tensile stress at break of gelatin (12%) fibers are raised about 2.2 and 1.9 times as those of gelatin (8%) fibers. The COMSOL simulations indicate that the sizes and cross-sections of the gelatin fibers can be tuned by using a microfluidic device with four-chevron grooves. The experimental results demonstrate that the decrease of the sheath-to-core flow-rate ratio from 150 : 1 to 30 : 1 can increase the aspect ratio and size of ribbon-shaped fibers from 35 μm × 60 μm to 47 μm × 282 μm, which is consistent with the simulation results. The increased size and shape evolution of the cross-section can not only strengthen the Young's modulus and tensile stress at break, but also significantly enhance the tensile strain at break.

Graphical abstract: On-chip development of hydrogel microfibers from round to square/ribbon shape

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Article information


Submitted
07 Nov 2013
Accepted
20 Jan 2014
First published
20 Jan 2014

J. Mater. Chem. A, 2014,2, 4878-4884
Article type
Communication

On-chip development of hydrogel microfibers from round to square/ribbon shape

Z. Bai, J. M. Mendoza Reyes, R. Montazami and N. Hashemi, J. Mater. Chem. A, 2014, 2, 4878
DOI: 10.1039/C3TA14573E

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