Monitoring the interaction of nucleolipoplexes with model membranes†
Abstract
We report on the interaction of nucleolipid/DNA assemblies with model membranes, studied with small angle X-ray scattering, fluorescence microscopy and correlation spectroscopy. The fusion with the membrane can be monitored by following the diffusion properties of a lipid probe, shedding light on the parameters that regulate the internalization of the complexes.