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Issue 5, 2014
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EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

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Abstract

Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Graphical abstract: EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

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Publication details

The article was received on 05 Nov 2013, accepted on 11 Dec 2013 and first published on 27 Jan 2014


Article type: Edge Article
DOI: 10.1039/C3SC53056F
Citation: Chem. Sci., 2014,5, 1750-1756

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    EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

    S. J. Butler, L. Lamarque, R. Pal and D. Parker, Chem. Sci., 2014, 5, 1750
    DOI: 10.1039/C3SC53056F

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