Issue 10, 2015
From the journal:

RSC Advances

Pyrroloquinoline quinone maintains redox activity when bound to a DNA aptamer†

Ismaila Emahi,a   Isabel M. Mulvihilla  and  Dana A. Baum*a  

* Corresponding authors

a Saint Louis University, Department of Chemistry, 3501 Laclede Avenue, St. Louis, Missouri, USA 63103
E-mail: dbaum1@slu.edu

Abstract

We have identified by in vitro selection DNA aptamers for the redox cofactor pyrroloquinoline quinone (PQQ). Using a spectroscopic assay, we determined PQQ maintains its redox properties when bound to the DNA aptamers. These complexes could find potential use as biocatalysts when direct electrical communication with electrode surfaces is desirable.

Graphical abstract: Pyrroloquinoline quinone maintains redox activity when bound to a DNA aptamer

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Article information

DOI
https://doi.org/10.1039/C4RA11052H
Article type
Communication
Submitted
23 Sep 2014
Accepted
18 Dec 2014
First published
22 Dec 2014

RSC Adv., 2015,5, 7450-7453

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Pyrroloquinoline quinone maintains redox activity when bound to a DNA aptamer

I. Emahi, I. M. Mulvihill and D. A. Baum, RSC Adv., 2015, 5, 7450 DOI: 10.1039/C4RA11052H

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