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Issue 108, 2014
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Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit

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Abstract

This study investigated the anti-insulin resistant activity of red pitaya (Hylocereus polyrhizus) fruit. Fresh pitaya along with two heat-processed pitaya samples with different proportions of phenolic contents, scavenging activities, and soluble dietary fibers were tested in insulin resistant rats over 6 weeks of treatment in a cause-effect study to investigate the anti-insulin resistant components of red pitaya. The results showed that fresh pitaya significantly (p < 0.05) attenuated the insulin resistance, hypertriglyceridemia and atherosclerotic changes induced by fructose supplement in rats. Thermally-treated pitaya at 95 °C for 30 min (containing a low antioxidant content) significantly (p < 0.05) improved hyperinsulinemia. Thermally-treated pitaya at 105 °C for 60 min (containing a low antioxidant and soluble dietary fiber content) fed to rats had no significant effect on insulin resistance, dyslipidemia and atherogenesis. Based on this study, the anti-insulin resistant effect of red pitaya can be attributed to its antioxidant and soluble dietary fiber contents.

Graphical abstract: Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit

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Article information


Submitted
19 Sep 2014
Accepted
14 Nov 2014
First published
14 Nov 2014

RSC Adv., 2014,4, 62978-62986
Article type
Paper
Author version available

Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit

A. Omidizadeh, R. M. Yusof, S. Roohinejad, A. Ismail, M. Z. Abu Bakar and A. El-Din A. Bekhit, RSC Adv., 2014, 4, 62978
DOI: 10.1039/C4RA10789F

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