Issue 89, 2014
From the journal:

RSC Advances

Lumazine synthase protein cage nanoparticles as modular delivery platforms for targeted drug delivery†

Junseon Min,a   Soohyun Kim,a   Jisu Leea  and  Sebyung Kang*a  

* Corresponding authors

a Department of Biological Sciences, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, Korea
E-mail: sabsab7@unist.ac.kr
Fax: +82-52-217-5309
Tel: +82-52-217-5325

Abstract

Lumazine synthase protein cage nanoparticle isolated from Aquifex aeolicus (AaLS) is developed as a modular delivery nanoplatform that genetically acquires either tumor vasculature targeting peptides or hepatocellular carcinoma cell surface targeting peptides on its surface. The targeting peptide bearing AaLS effectively delivers its cargo to their target cancer cells.

Graphical abstract: Lumazine synthase protein cage nanoparticles as modular delivery platforms for targeted drug delivery

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Article information

DOI
https://doi.org/10.1039/C4RA10187A
Article type
Communication
Submitted
11 Sep 2014
Accepted
24 Sep 2014
First published
25 Sep 2014

RSC Adv., 2014,4, 48596-48600

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Lumazine synthase protein cage nanoparticles as modular delivery platforms for targeted drug delivery

J. Min, S. Kim, J. Lee and S. Kang, RSC Adv., 2014, 4, 48596 DOI: 10.1039/C4RA10187A

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