A novel, simple, and cost-effective copper-catalyzed direct cyanoalkylarylation of activated alkenes with AIBN has been developed with cheap K2S2O8 as the oxidant. A series of cyano-containing oxindoles that are otherwise difficult to obtain through previous methods were efficiently synthesized using this protocol.
W. Wei, J. Wen, D. Yang, M. Guo, L. Tian, J. You and H. Wang, RSC Adv., 2014, 4, 48535 DOI: 10.1039/C4RA09022E
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