Issue 70, 2014
From the journal:

RSC Advances

Continuous flow synthesis of β-amino acids from α-amino acids via Arndt–Eistert homologation†

Vagner D. Pinho,a   Bernhard Gutmanna  and  C. Oliver Kappe*a  

* Corresponding authors

a Institute of Chemistry, University of Graz, NAWI Graz, Heinrichstrasse 28, A-8010 Graz, Austria
E-mail: oliver.kappe@uni-graz.at

Abstract

A fully continuous four step process for the preparation of β-amino acids from their corresponding α-amino acids utilizing the Arndt–Eistert homologation approach is described.

Graphical abstract: Continuous flow synthesis of β-amino acids from α-amino acids via Arndt–Eistert homologation

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Article information

DOI
https://doi.org/10.1039/C4RA08113G
Article type
Communication
Submitted
02 Jul 2014
Accepted
12 Aug 2014
First published
13 Aug 2014

RSC Adv., 2014,4, 37419-37422

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Continuous flow synthesis of β-amino acids from α-amino acids via Arndt–Eistert homologation

V. D. Pinho, B. Gutmann and C. O. Kappe, RSC Adv., 2014, 4, 37419 DOI: 10.1039/C4RA08113G

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