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Issue 94, 2014
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Enhanced oxidized regenerated cellulose with functionalized multiwalled carbon nanotubes for hemostasis applications

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Abstract

Oxidized Regenerated Cellulose (ORC) has been modified by incorporating aminated MWCNTs (MWCNT-NH2)s. The pristine MWCNTs (pMWCNTs) were aminated which introduced aromatic amine groups on the side walls of the MWCNTs. For modification of neat ORC, the MWCNT-NH2s were reacted with neat ORC. To explore the origin of this behavior, amination of MWCNTs, dispersion of MWCNT-NH2s in the ORC matrix and their interfacial interactions were investigated by SEM, FT-IR and XPS. The analytical results show that during functionalization of the MWCNTs, the amine groups grafted onto the surface of the MWCNTs. In addition, the FT-IR and XPS results revealed that a relatively strong interaction existed between the aminated MWCNTs and the ORC macromolecules. The hydrophilicity test results revealed a significant increment in water uptake of the MWCNT-NH2s/ORC composites with increasing concentration of MWCNT-NH2s in the composites. The haemostatic evaluation of the MWCNT-NH2s/ORC composites in rabbits shows that the aminated MWCNTs increase the rate of blood stopping and hence decrease the blood loss from injured sites.

Graphical abstract: Enhanced oxidized regenerated cellulose with functionalized multiwalled carbon nanotubes for hemostasis applications

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Article information


Submitted
28 Jul 2014
Accepted
13 Oct 2014
First published
13 Oct 2014

RSC Adv., 2014,4, 52372-52378
Article type
Paper
Author version available

Enhanced oxidized regenerated cellulose with functionalized multiwalled carbon nanotubes for hemostasis applications

A. N. Chakoli, J. He, W. Cheng and Y. Huang, RSC Adv., 2014, 4, 52372
DOI: 10.1039/C4RA07704K

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