Asymmetric synthesis towards doxanthrine, a dopamine D1 full agonist†
Abstract
Asymmetric synthesis of O-methyl doxanthrine is accomplished with high diastereo- and enantioselectivity from β-aryloxyamino acid derived from D-serine.
* Corresponding authors
a Department of Chemistry, Guru Jambheshwar University of Science and Technology, Hisar, Haryana 125001, India
b
TCG Life Sciences Ltd, Saltlake, Kolkata 700091, India
E-mail:
sourav@chembiotek.com
Fax: +91-33-23673058
Tel: +91-33-23673151
c
Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur 721302, India
E-mail:
shajra@chem.iitkgp.ernet.in
Fax: +91-3222-282252
Tel: +91-3222-283340
d
Centre of Biomedical Research, SGPGIMS Campus, Lucknow 226014, India
E-mail:
saumen.hajra@cbmr.res.in
Asymmetric synthesis of O-methyl doxanthrine is accomplished with high diastereo- and enantioselectivity from β-aryloxyamino acid derived from D-serine.
R. Malhotra, A. Ghosh, S. Dutta, T. K. Dey, S. Basu and S. Hajra, RSC Adv., 2014, 4, 48344 DOI: 10.1039/C4RA06617K
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