Issue 51, 2014

Copper-catalyzed cascade reactions of N-(2-bromoallyl)amines with KHCO3 as the C1 source: an efficient process for the synthesis of oxazolidin-2-ones

Abstract

A novel synthesis of oxazolidin-2-ones by carbamic acid formation and a subsequent copper-catalyzed intramolecular vinylation from N-(2-bromoallyl)amines and KHCO3 was developed. KHCO3 was used as a C1 source and base in this efficient and convenient cascade process.

Graphical abstract: Copper-catalyzed cascade reactions of N-(2-bromoallyl)amines with KHCO3 as the C1 source: an efficient process for the synthesis of oxazolidin-2-ones

Supplementary files

Article information

Article type
Communication
Submitted
21 Mar 2014
Accepted
28 Apr 2014
First published
28 Apr 2014

RSC Adv., 2014,4, 26990-26992

Copper-catalyzed cascade reactions of N-(2-bromoallyl)amines with KHCO3 as the C1 source: an efficient process for the synthesis of oxazolidin-2-ones

H. Jin, Y. Yang, J. Jia, B. Yue, B. Lang and J. Weng, RSC Adv., 2014, 4, 26990 DOI: 10.1039/C4RA02304H

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