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A Pd-catalyzed cascade Ullmann coupling–aldol–dehydration reaction of ortho-acylphenyl iodides has been explored. This transformation provides a concise access to colchino analogues in moderate to good yields with wide functional group tolerance.

Graphical abstract: Pd-catalyzed tandem homocoupling–aldol–dehydration of ortho-acylphenyl iodides

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