Issue 31, 2014

Cascade synthesis of novel functionalized pyridine-fused coumarins in aqueous medium

Abstract

A simple, convenient and efficient catalyst-free approach for synthesis of a novel series of functionalized pyridine-fused coumarins via a cascade reaction from chromone derivatives in an environmentally friendly aqueous medium has been developed. This cascade reaction involves a chemoselective Michael addition–heterocyclization-intramolecular cyclization sequence.

Graphical abstract: Cascade synthesis of novel functionalized pyridine-fused coumarins in aqueous medium

Supplementary files

Article information

Article type
Paper
Submitted
03 Mar 2014
Accepted
24 Mar 2014
First published
25 Mar 2014

RSC Adv., 2014,4, 16132-16135

Cascade synthesis of novel functionalized pyridine-fused coumarins in aqueous medium

H. Xiang, J. Chen, Z. Miao and C. Yang, RSC Adv., 2014, 4, 16132 DOI: 10.1039/C4RA01848F

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