Chada Raji Reddy and Paridala Kumaraswamy
RSC Adv., 2014,4, 7035-7040
DOI:
10.1039/C3RA46229C,
Paper
One-pot synthesis of substituted cyclopentenes was accomplished through a copper-mediated [4 + 1]-annulation of active methylene compounds with Morita–Baylis–Hillman (MBH) acetates of acetylenic aldehydes. The reaction sequence involves the cascade allylic substitution/5-exo-dig-carbocyclization, which was effective in providing methylene, alkylidene as well as arylidene cyclopentenes.
