Jump to main content
Jump to site search

Issue 10, 2014
Previous Article Next Article

Development of sustainable fluorous chemistry: the synthesis and characterization of fluorous ethers with nonafluoro-tert-butoxy groups

Author affiliations

Abstract

Nonafluoro-t-butyl propyl (1), allyl (2), and propargyl (3) ethers as well as 1,2-bis(nonafluoro-t-butoxy)ethane (4), 1,3-bis(nonafluoro-t-butoxy)-propane (5), and 1,4-bis(nonafluoro-t-butoxy)-butane (6) were prepared by the reaction of sodium nonafluoro-t-butoxide (7) with the corresponding alkyl halides in good yields. Their fluorous partition coefficients and toxicity were also investigated. Computational studies have shown that 4, 5 and 6 exist in a monomeric form in MeOH–CF3C6F11 and they likely aggregate to form oligomers in PhCH3–CF3C6F11.

Graphical abstract: Development of sustainable fluorous chemistry: the synthesis and characterization of fluorous ethers with nonafluoro-tert-butoxy groups

Back to tab navigation

Supplementary files

Publication details

The article was received on 08 Jul 2014, accepted on 23 Sep 2014 and first published on 13 Oct 2014


Article type: Research Article
DOI: 10.1039/C4QO00192C
Citation: Org. Chem. Front., 2014,1, 1180-1187
  •   Request permissions

    Development of sustainable fluorous chemistry: the synthesis and characterization of fluorous ethers with nonafluoro-tert-butoxy groups

    S. Lo, E. Law, M. Y. Lui, X. Wei, K. Lau, C. Y. Ma, M. B. Murphy and I. T. Horváth, Org. Chem. Front., 2014, 1, 1180
    DOI: 10.1039/C4QO00192C

Search articles by author

Spotlight

Advertisements