Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 5, 2016
Previous Article Next Article

Smart block copolymers of PVP and an alkylated PVP derivative: synthesis, characterization, thermoresponsive behaviour and self-assembly

Author affiliations

Abstract

Stimuli responsive block copolymers of biocompatible poly(3-ethyl-N-vinylpyrrolidone) and poly(N-vinylpyrrolidone), i.e. EPVP–PVP, were readily synthesized via RAFT-mediated polymerization. The thermoresponsive behaviour and temperature induced self-assembly, in aqueous solutions, was studied using various spectroscopic and microscopy techniques. We obtained different morphologies, i.e. spherical and cylindrical micelles, and vesicles, via temperature induced self-assembly, of aqueous solutions of a single diblock copolymer by simply adjusting the solution concentration. This study establishes the biocompatible EPVP/PVP combination as a versatile stimuli responsive block copolymer system suitable for applications in drug delivery.

Graphical abstract: Smart block copolymers of PVP and an alkylated PVP derivative: synthesis, characterization, thermoresponsive behaviour and self-assembly

Back to tab navigation

Supplementary files

Article information


Submitted
06 Oct 2015
Accepted
22 Dec 2015
First published
23 Dec 2015

Polym. Chem., 2016,7, 1138-1146
Article type
Paper
Author version available

Smart block copolymers of PVP and an alkylated PVP derivative: synthesis, characterization, thermoresponsive behaviour and self-assembly

J. Giliomee, R. Pfukwa, N. P. Gule and B. Klumperman, Polym. Chem., 2016, 7, 1138
DOI: 10.1039/C5PY01609F

Social activity

Search articles by author

Spotlight

Advertisements