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Abstract | Cited by

A truly novel strategy for fabricating reducible supramolecular assemblies based on the host–guest interaction between cucurbit[8]uril (CB[8]) and methyl viologen (MV) is reported. The anticancer drug doxorubicin is loaded into the assemblies and a reducing agent Na2S2O4 can be used to successfully trigger release of drugs because of the redox chemistry of MV.

Graphical abstract: Biocompatible and biodegradable supramolecular assemblies formed with cucurbit[8]uril as a smart platform for reduction-triggered release of doxorubicin

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