Jump to main content
Jump to site search

Issue 31, 2014
Previous Article Next Article

One-pot synthesis of polysubstituted 3-acylpyrroles by cooperative catalysis

Author affiliations

Abstract

One-pot syntheses of polysubstituted 3-acylpyrroles from readily available unsaturated ketones and N-substituted propargylated amines have been developed. An aza-Michael/alkyne carbocyclization cascade, by cooperative catalysis using pyrrolidine and a copper salt, followed by oxidation in situ gave 3-acylpyrroles, which were also transformed further to functionalized, highly substituted 3-acylpyrroles.

Graphical abstract: One-pot synthesis of polysubstituted 3-acylpyrroles by cooperative catalysis

Back to tab navigation

Supplementary files

Article information


Submitted
17 May 2014
Accepted
17 Jun 2014
First published
17 Jun 2014

Org. Biomol. Chem., 2014,12, 5822-5826
Article type
Communication
Author version available

One-pot synthesis of polysubstituted 3-acylpyrroles by cooperative catalysis

H. Cui and F. Tanaka, Org. Biomol. Chem., 2014, 12, 5822
DOI: 10.1039/C4OB01019A

Social activity

Search articles by author

Spotlight

Advertisements