Michael N. Gandy, Colin L. Raston and Keith A. Stubbs
Org. Biomol. Chem., 2014,12, 4594-4597
DOI:
10.1039/C4OB00926F,
Communication
C–N bond forming reactions are important in organic chemistry. A thin film microfluidic vortex fluidic device (VFD) operating under confined mode affords N-aryl compounds from 2-chloropyrazine and the corresponding amine, without the need for a transition metal catalyst.