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Issue 35, 2014
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A one-pot synthetic strategy for construction of the dibenzodiazepine skeleton via a transition metal-free process

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Abstract

A one-pot transition metal-free methodology for constructing pharmacologically active dibenzodiazepine derivatives was developed. Fluoro-, bromo- and nitro-substituted aryl aldehydes were applied to this reaction efficiently.

Graphical abstract: A one-pot synthetic strategy for construction of the dibenzodiazepine skeleton via a transition metal-free process

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Article information


Submitted
30 Apr 2014
Accepted
13 Jul 2014
First published
15 Jul 2014

Org. Biomol. Chem., 2014,12, 6895-6900
Article type
Paper

A one-pot synthetic strategy for construction of the dibenzodiazepine skeleton via a transition metal-free process

S. Fang, X. Niu, Z. Zhang, Y. Sun, X. Si, C. Shan, L. Wei, A. Xu, L. Feng and C. Ma, Org. Biomol. Chem., 2014, 12, 6895
DOI: 10.1039/C4OB00871E

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