Brian M. Muller, Jesse Mai, Reid A. Yocum and Marc J. Adler
Org. Biomol. Chem., 2014,12, 5108-5114
DOI:
10.1039/C4OB00398E,
Paper
The effect of aryl substitution on various aspects of the interconversion of ortho-hydroxychalcones and flavanones has been studied using multiple spectroscopic techniques. Derivatization of the core scaffold predictably alters the midpoint pH of this equilibration process suggesting its viability for application as a functional colorimetric molecular switch.