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Issue 17, 2014
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Synthesis of a multibranched porphyrin–oligonucleotide scaffold for the construction of DNA-based nano-architectures

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Abstract

The interest in the functionalization of oligonucleotides with organic molecules has grown considerably over the last decade. In this work, we report on the synthesis and characterization of porphyrin–oligonucleotide hybrids containing one to four DNA strands (P1–P4). The hybrid P4, which inserts one porphyrin and four DNA fragments, was combined with gold nanoparticles and imaged by transmission electron microscopy.

Graphical abstract: Synthesis of a multibranched porphyrin–oligonucleotide scaffold for the construction of DNA-based nano-architectures

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Article information


Submitted
25 Jan 2014
Accepted
25 Feb 2014
First published
25 Feb 2014

Org. Biomol. Chem., 2014,12, 2778-2783
Article type
Paper
Author version available

Synthesis of a multibranched porphyrin–oligonucleotide scaffold for the construction of DNA-based nano-architectures

G. Clavé, G. Chatelain, A. Filoramo, D. Gasparutto, C. Saint-Pierre, E. Le Cam, O. Piétrement, V. Guérineau and S. Campidelli, Org. Biomol. Chem., 2014, 12, 2778
DOI: 10.1039/C4OB00202D

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