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Issue 14, 2014
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Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry

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Abstract

The use of state-of-the-art separation tools from the pharmaceutical industry for addressing intractable separation problems from academic synthetic chemistry is evaluated, showing fast and useful results for the resolution of complex mixtures, separation of closely related components, visualization of difficult to detect compounds and purification of synthetic intermediates. Some recommendations for potential near term deployment of separation tools within academia and the evolution of next generation separation technologies are discussed.

Graphical abstract: Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry

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Supplementary files

Article information


Submitted
06 Nov 2013
Accepted
20 Feb 2014
First published
20 Feb 2014

Org. Biomol. Chem., 2014,12, 2161-2166
Article type
Review Article

Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry

E. L. Regalado, M. C. Kozlowski, J. M. Curto, T. Ritter, M. G. Campbell, A. R. Mazzotti, B. C. Hamper, C. D. Spilling, M. P. Mannino, L. Wan, J. Yu, J. Liu and C. J. Welch, Org. Biomol. Chem., 2014, 12, 2161
DOI: 10.1039/C3OB42195C

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