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Issue 5, 2014
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Chiral Brønsted acid-catalyzed enantioselective addition of indoles to ketimines

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Abstract

A highly enantioselective addition of indoles to a readily available ketimine was found to be catalyzed by a chiral phosphoric acid. This organocatalytic process represents a rare example of an addition reaction to a non-aromatic ketimine.

Graphical abstract: Chiral Brønsted acid-catalyzed enantioselective addition of indoles to ketimines

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Article information


Submitted
05 Nov 2013
Accepted
26 Nov 2013
First published
27 Nov 2013

Org. Biomol. Chem., 2014,12, 724-727
Article type
Communication

Chiral Brønsted acid-catalyzed enantioselective addition of indoles to ketimines

T. Kano, R. Takechi, R. Kobayashi and K. Maruoka, Org. Biomol. Chem., 2014, 12, 724
DOI: 10.1039/C3OB42190B

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