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Issue 11, 2016
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Polymeric near-infrared absorbing dendritic nanogels for efficient in vivo photothermal cancer therapy

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Abstract

In recent years, several near-infrared light absorbing inorganic nanomaterials have been developed for photothermal therapy. However, their biological fate after injection limits their clinical utilization. In this work, we developed a novel polymeric near-infrared light absorbing material based on a biocompatible thermoresponsive nanogel that is semi-interpenetrated with polyaniline, a conjugated polymer with strong near-infrared absorbance. This polymeric nanocomposite generates heat after being irradiated by NIR light, thereby inducing a local hyperthermia that is used for photothermal cancer therapy in vitro and in vivo.

Graphical abstract: Polymeric near-infrared absorbing dendritic nanogels for efficient in vivo photothermal cancer therapy

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Supplementary files

Article information


Submitted
30 Oct 2015
Accepted
21 Feb 2016
First published
22 Feb 2016

This article is Open Access

Nanoscale, 2016,8, 5852-5856
Article type
Communication

Polymeric near-infrared absorbing dendritic nanogels for efficient in vivo photothermal cancer therapy

M. Molina, S. Wedepohl and M. Calderón, Nanoscale, 2016, 8, 5852
DOI: 10.1039/C5NR07587D

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    [Original citation] - Published by The Royal Society of Chemistry.

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