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Issue 1, 2015
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Supported lipid bilayers as dynamic platforms for tethered particles

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Abstract

Nanoparticle tethering to lipid bilayers enables the observation of hundreds of diffusing particles that are confined within a single field of view. A wide variety of materials ranging from plasmonic metals to soft matter can be stably tethered to the surface of a fluid bilayer by covalent or non-covalent means. The controlled environment of this experimental platform allows direct control over surface compositions and accurate tracking of nanoparticle interactions. This minireview will cover studies that use bilayer-tethered nanoparticles to investigate physical properties related to lipid mobility, biomolecule sensing, and surface interactions, as well as experiments to reversibly manipulate tethered nanoparticles by electric fields.

Graphical abstract: Supported lipid bilayers as dynamic platforms for tethered particles

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Article information


Submitted
23 Sep 2014
Accepted
20 Oct 2014
First published
23 Oct 2014

Nanoscale, 2015,7, 66-76
Article type
Minireview

Supported lipid bilayers as dynamic platforms for tethered particles

K. L. Hartman, S. Kim, K. Kim and J. Nam, Nanoscale, 2015, 7, 66
DOI: 10.1039/C4NR05591H

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