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Issue 23, 2014
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Plasmonic caged gold nanorods for near-infrared light controlled drug delivery

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Abstract

A new near-infrared light-controlled drug delivery system based on caged gold nanorods (CGNRs) is demonstrated. The loading and release process of drug payloads into/from CGNR nanocarriers were systematically investigated. The drug-loaded CGNR constructs could enable combined chemotherapy and photo-thermal effects in killing tumor cells upon light irradiation, therefore, enhance the killing efficiency. In conjunction with visibility under quenching-free dark-field imaging, CGNRs may serve as multifunctional theranostic reagents towards cancer diagnostics and therapeutics.

Graphical abstract: Plasmonic caged gold nanorods for near-infrared light controlled drug delivery

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Supplementary files

Article information


Submitted
01 Aug 2014
Accepted
16 Sep 2014
First published
18 Sep 2014

Nanoscale, 2014,6, 14388-14393
Article type
Paper

Plasmonic caged gold nanorods for near-infrared light controlled drug delivery

W. Xiong, R. Mazid, L. W. Yap, X. Li and W. Cheng, Nanoscale, 2014, 6, 14388
DOI: 10.1039/C4NR04400B

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