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Issue 16, 2014
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Coiled fiber scaffolds embedded with gold nanoparticles improve the performance of engineered cardiac tissues

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Abstract

Coiled perimysial fibers within the heart muscle provide it with the ability to contract and relax efficiently. Here, we report on a new nanocomposite scaffold for cardiac tissue engineering, integrating coiled electrospun fibers with gold nanoparticles. Cultivation of cardiac cells within the hybrid scaffolds promoted cell organization into elongated and aligned tissues generating a strong contraction force, high contraction rate and low excitation threshold.

Graphical abstract: Coiled fiber scaffolds embedded with gold nanoparticles improve the performance of engineered cardiac tissues

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Article information


Submitted
16 Jan 2014
Accepted
09 Mar 2014
First published
12 Mar 2014

Nanoscale, 2014,6, 9410-9414
Article type
Communication
Author version available

Coiled fiber scaffolds embedded with gold nanoparticles improve the performance of engineered cardiac tissues

S. Fleischer, M. Shevach, R. Feiner and T. Dvir, Nanoscale, 2014, 6, 9410
DOI: 10.1039/C4NR00300D

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