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Issue 16, 2014
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Plasmonic ELISA for the detection of gp120 at ultralow concentrations with the naked eye

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Abstract

The technique of plasmonic ELISA is utilised here to detect the HIV-1 protein gp120 with the ultralow limit of detection of 8 × 10−20 M (1017 g mL−1) in an independent laboratory. It was corroborated that changes in the concentration of hydrogen peroxide as small as 0.05 μM could lead to nanoparticle solutions of completely different tonality.

Graphical abstract: Plasmonic ELISA for the detection of gp120 at ultralow concentrations with the naked eye

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Article information


Submitted
20 Nov 2013
Accepted
11 Apr 2014
First published
05 May 2014

Nanoscale, 2014,6, 9559-9562
Article type
Communication
Author version available

Plasmonic ELISA for the detection of gp120 at ultralow concentrations with the naked eye

D. Cecchin, R. de la Rica, R. E. S. Bain, M. W. Finnis, M. M. Stevens and G. Battaglia, Nanoscale, 2014, 6, 9559
DOI: 10.1039/C3NR06167A

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