Julian Egger and Erick M. Carreira
Nat. Prod. Rep., 2014,31, 449-455
DOI:
10.1039/C3NP70084D,
Highlight
Covering: up to April 2013
Transition metal-catalyzed insertion of carbenes and nitrenes into C–H bonds has become a powerful tool for the construction of C–C and C–N bonds in the synthesis of complex natural products. In this Highlight, a selection of syntheses are detailed involving the implementation of C–H insertion reactions leading to strategies marked by improved efficiency.